The Idea: In 2011, Keller Rinaudo Cliffton was building smartphone-controlled toy robots at a company called Romotive. The product was cute, but it wasn't changing lives. After Romotive shut down in 2014, Keller gathered his co-founders - Keenan Wyrobek, Ryan Oksenhorn, and Will Hetzler - and asked a different question: What if drones could deliver medicine to people who couldn't get it any other way? They pitched the government of Rwanda, a small country with mountainous terrain and poor roads where blood shortages killed patients daily. Rwanda said yes. For their first year, Zipline served exactly one hospital. Their drones crashed. Their systems failed. The government was patient. Keller's bet was that if they could prove drones could save lives at national scale in Africa, the rest of the world would follow. This was the beginning of Zipline.

The Execution:

The lesson? Keller didn't start with the biggest market - he started with the market that needed him most. Rwanda's difficult terrain and urgent healthcare needs made it the perfect proving ground. Seven years later, that bet unlocked partnerships with Walmart, Panera, and the Mayo Clinic. Sometimes the best path to dominating developed markets is proving your technology where it's needed most.